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NV Alpha Arbutin

Facial

Características

1. Ativos

Alpha-arbutin

2. Claims

Whitening and uniformity of skin tone;
Assistance in the treatment of melasma;
Helps maintain skin elasticity;
Antioxidant effect.

3. Aplicação

Creams;
gels;
cream gels;
serums;
emulsions in general.

4. Propriedades

Vegan
Cruelty-free

NV Alpha Arbutin

NV ALPHA ARBUTIN contains alpha-arbutin, a safer derivative of hydroquinone that works by blocking the synthesis of melanin at the applied site. The alpha-arbutin input is quite unstable to heat and has low skin permeation, deficiencies corrected with the use of Nanovetores lipid nanoparticles, which also provide sensorial and prolonged release qualities to the active ingredient.

It is a powerful depigmenting agent, promoting whitening and uniformity of all skin types, reducing pre-existing spots and preventing the appearance of new spots.

Descrição do Ativo

Arbutin is a hydroquinone glucoside compound of plant origin found in several plants, such as pears, blackberries and blueberries. It has two isomers, alpha (4-hydroxyphenyl α-D-glucopyranoside) and beta (4-hydroxyphenyl β-D-glucopyranoside), where only the β isomer is naturally occurring in plants, with the α isomer being synthesized by enzymes from microorganisms. . Both isomers act as skin lighteners, but the compound in its alpha form is about 10 times more efficient, due to its greater affinity with the active site on the skin, tyrosinase, which is why it is the compound used in the formulation of NV ALPHA ARBUTIN.

The mechanism of action of alpha arbutin is through the inhibition of the tyrosinase enzyme, responsible for the production and regulation of melanin in the skin, similarly to the action of hydroquinone, but without presenting toxicity, suggesting that the size of the molecule and the electrostatic action of the aromatic ring They strongly influence the functioning of tyrosinase, which is inhibited by having its transcriptase affected. Other mechanisms of α-arbutin in regulating melanin include antioxidant action, acceleration of epidermal renewal and anti-inflammatory action. Melanin regulation also helps in the treatment of melasma.

The European Scientific Committee on Consumer Safety (SCCS) confirms that α-arbutin is safe and effective as a skin lightener, having no cytotoxicity and causing considerably less irritation and melanotoxicity than one of the most famous lighteners, hydroquinone. In addition to being whitening, α-arbutin brings other benefits, such as reducing the degree of tanning without increasing skin sensitivity after sun exposure and helping to correct glycation, skin paleness and loss of elasticity. However, even with all the benefits it brings, α-arbutin is quite hydrophilic, which considerably compromises its permeability capacity on the skin, and also has to be formulated at low temperatures due to its instability to heat, reducing its effectiveness and ease. of production. A useful strategy in reversing these deficiencies of α-arbutin is its nanoencapsulation, improving its stability, bioavailability and even increasing its whitening effect. Therefore, NV ALPHA ARBUTIN is the ideal solution in the search for whitening products, bringing several benefits to the skin and the effectiveness and stability provided by NANOVETORES nanotechnology.

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